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Accumulation of Rhodopsin in Late Endosomes Triggers Photoreceptor Cell Degeneration
Progressive retinal degeneration is the underlying feature of many human retinal dystrophies. Previous work using Drosophila as a model system and analysis of specific mutations in human rhodopsin have uncovered a connection between rhodopsin endocytosis and retinal degeneration. In these mutants, r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633617/ https://ncbi.nlm.nih.gov/pubmed/19214218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000377 |
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