The CUL7 E3 Ubiquitin Ligase Targets Insulin Receptor Substrate 1 for Ubiquitin-Dependent Degradation

Recent genetic studies have documented a pivotal growth-regulatory role played by the Cullin 7 (CUL7) E3 ubiquitin ligase complex containing the Fbw8-substrate-targeting subunit, Skp1, and the ROC1 RING finger protein. In this report, we identified insulin receptor substrate 1 (IRS-1), a critical me...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Xu, Xinsong, Sarikas, Antonio, Dias-Santagata, Dora C., Dolios, Georgia, Lafontant, Pascal J., Tsai, Shih-Chong, Zhu, Wuqiang, Nakajima, Hidehiro, Nakajima, Hisako O., Field, Loren J., Wang, Rong, Pan, Zhen-Qiang
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633441/
https://ncbi.nlm.nih.gov/pubmed/18498745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.03.009
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars