Stwl Modifies Chromatin Compaction and Is Required to Maintain DNA Integrity in the Presence of Perturbed DNA Replication

Hydroxyurea, a well-known DNA replication inhibitor, induces cell cycle arrest and intact checkpoint functions are required to survive DNA replication stress induced by this genotoxic agent. Perturbed DNA synthesis also results in elevated levels of DNA damage. It is unclear how organisms prevent ac...

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Bibliografiske detaljer
Main Authors: Yi, Xia, de Vries, Hilda I., Siudeja, Katarzyna, Rana, Anil, Lemstra, Willy, Brunsting, Jeanette F., Kok, Rob M., Smulders, Yvo M., Schaefer, Matthias, Dijk, Freark, Shang, Yongfeng, Eggen, Bart J.L., Kampinga, Harm H., Sibon, Ody C.M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633405/
https://ncbi.nlm.nih.gov/pubmed/19056684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0639
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