Stwl Modifies Chromatin Compaction and Is Required to Maintain DNA Integrity in the Presence of Perturbed DNA Replication

Hydroxyurea, a well-known DNA replication inhibitor, induces cell cycle arrest and intact checkpoint functions are required to survive DNA replication stress induced by this genotoxic agent. Perturbed DNA synthesis also results in elevated levels of DNA damage. It is unclear how organisms prevent ac...

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Autores principales: Yi, Xia, de Vries, Hilda I., Siudeja, Katarzyna, Rana, Anil, Lemstra, Willy, Brunsting, Jeanette F., Kok, Rob M., Smulders, Yvo M., Schaefer, Matthias, Dijk, Freark, Shang, Yongfeng, Eggen, Bart J.L., Kampinga, Harm H., Sibon, Ody C.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633405/
https://ncbi.nlm.nih.gov/pubmed/19056684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0639
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