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Increased resistance to CD4(+)CD25(hi) regulatory T cell-mediated suppression in patients with type 1 diabetes
Type I diabetes (T1D) is a T cell-mediated autoimmune disease characterized by loss of tolerance to islet autoantigens, leading to the destruction of insulin-producing beta cells. Peripheral tolerance to self is maintained in health through several regulatory mechanisms, including a population of CD...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633239/ https://ncbi.nlm.nih.gov/pubmed/19037920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03810.x |
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