Single cell analysis of B lymphocytes from Wegener's granulomatosis: B cell receptors display affinity maturation within the granulomatous lesions

Increased amounts of anti-neutrophil cytoplasm antibody (ANCA) directed against proteinase 3 (PR3) are a diagnostic and pathogenic hallmark of full-blown Wegener's granulomatosis (WG). Aggregates of B lymphocytes proximal to PR3(+) cells as well as plasma cells have been described as substantia...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Voswinkel, J, Assmann, G, Held, G, Pitann, S, Gross, W L, Holl-Ulrich, K, Herlyn, K, Mueller, A
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 2008
נושאים:
Translational Studies
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633232/
https://ncbi.nlm.nih.gov/pubmed/18826496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03775.x
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים