B lymphocyte maturation in Wegener's granulomatosis: a comparative analysis of VH genes from endonasal lesions

BACKGROUND: Anti‐neutrophil cytoplasmic antibodies (ANCA) directed against proteinase 3 (PR3) are highly specific for Wegener's granulomatosis (WG). Evidence for a pivotal role of PR3‐ANCA in the induction of vasculitis has been demonstrated. B cell clusters have been observed within endonasal...

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Detalhes bibliográficos
Main Authors: Voswinkel, J, Mueller, A, Kraemer, J A, Lamprecht, P, Herlyn, K, Holl‐Ulrich, K, Feller, A C, Pitann, S, Gause, A, Gross, W L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798221/
https://ncbi.nlm.nih.gov/pubmed/16291812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.044909
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