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CD28 negative T cells are enriched in granulomatous lesions of the respiratory tract in Wegener's granulomatosis

BACKGROUND—Lack of CD28 expression on peripheral blood CD4+ and CD8+ T cells has been reported in patients with Wegener's granulomatosis (WG), suggesting a pathogenetic role of CD28- T cells in WG.
METHODS—Ten patients with WG and six with sarcoidosis (disease control) were analysed. Fluorescen...

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Bibliographic Details
Main Authors: Lamprecht, P, Moosig, F, Csernok, E, Seitzer, U, Schnabel, A, Mueller, A, Gross, W
Format: Artigo
Language:Inglês
Published: BMJ Group 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745938/
https://ncbi.nlm.nih.gov/pubmed/11562512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.56.10.751
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