Identification of cyclic peptides able to mimic the functional epitope of IgG1-Fc for human FcγRI

Identification of short, structured peptides able to mimic potently protein-protein interfaces remains a challenge in drug discovery. We report here the use of a naive cyclic peptide phage display library to identify peptide ligands able to recognize and mimic IgG1-Fc functions with FcγRI. Selection...

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Detaylı Bibliyografya
Asıl Yazarlar: Bonetto, Stephane, Spadola, Loredana, Buchanan, Andrew G., Jermutus, Lutz, Lund, John
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Federation of American Societies for Experimental Biology 2009
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633172/
https://ncbi.nlm.nih.gov/pubmed/18957574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-117069
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