In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity α6* Nicotinic Acetylcholine Receptors

α6-containing (α6*) nicotinic ACh receptors (nAChRs) are selectively expressed in dopamine (DA) neurons and participate in cholinergic transmission. We generated and studied mice with gain-of-function α6* nAChRs, which isolate and amplify cholinergic control of DA transmission. In contrast to gene k...

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Autors principals: Drenan, Ryan M., Grady, Sharon R., Whiteaker, Paul, McClure-Begley, Tristan, McKinney, Sheri, Miwa, Julie M., Bupp, Sujata, Heintz, Nathaniel, McIntosh, J. Michael, Bencherif, Merouane, Marks, Michael J., Lester, Henry A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632732/
https://ncbi.nlm.nih.gov/pubmed/18940593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.09.009
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