Chronic Nicotine Cell Specifically Upregulates Functional α4* Nicotinic Receptors: Basis for Both Tolerance in Midbrain and Enhanced Long-Term Potentiation in Perforant Path

Understanding effects of chronic nicotine requires identifying the neurons and synapses whose responses to nicotine itself, and to endogenous acetylcholine, are altered by continued exposure to the drug. To address this problem, we developed mice whose α4 nicotinic receptor subunits are replaced by...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nashmi, Raad, Xiao, Cheng, Deshpande, Purnima, McKinney, Sheri, Grady, Sharon R., Whiteaker, Paul, Huang, Qi, McClure-Begley, Tristan, Lindstrom, Jon M., Labarca, Cesar, Collins, Allan C., Marks, Michael J., Lester, Henry A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673074/
https://ncbi.nlm.nih.gov/pubmed/17670967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2199-07.2007
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