Chronic Nicotine Cell Specifically Upregulates Functional α4* Nicotinic Receptors: Basis for Both Tolerance in Midbrain and Enhanced Long-Term Potentiation in Perforant Path

Understanding effects of chronic nicotine requires identifying the neurons and synapses whose responses to nicotine itself, and to endogenous acetylcholine, are altered by continued exposure to the drug. To address this problem, we developed mice whose α4 nicotinic receptor subunits are replaced by...

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Publicado en:J Neurosci
Autores principales: Nashmi, Raad, Xiao, Cheng, Deshpande, Purnima, McKinney, Sheri, Grady, Sharon R., Whiteaker, Paul, Huang, Qi, McClure-Begley, Tristan, Lindstrom, Jon M., Labarca, Cesar, Collins, Allan C., Marks, Michael J., Lester, Henry A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2007
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673074/
https://ncbi.nlm.nih.gov/pubmed/17670967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2199-07.2007
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