Chronic Nicotine Cell Specifically Upregulates Functional α4* Nicotinic Receptors: Basis for Both Tolerance in Midbrain and Enhanced Long-Term Potentiation in Perforant Path

Understanding effects of chronic nicotine requires identifying the neurons and synapses whose responses to nicotine itself, and to endogenous acetylcholine, are altered by continued exposure to the drug. To address this problem, we developed mice whose α4 nicotinic receptor subunits are replaced by...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Nashmi, Raad, Xiao, Cheng, Deshpande, Purnima, McKinney, Sheri, Grady, Sharon R., Whiteaker, Paul, Huang, Qi, McClure-Begley, Tristan, Lindstrom, Jon M., Labarca, Cesar, Collins, Allan C., Marks, Michael J., Lester, Henry A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673074/
https://ncbi.nlm.nih.gov/pubmed/17670967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2199-07.2007
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