Cholinergic Modulation of Locomotion and Striatal Dopamine Release Is Mediated by α6α4* Nicotinic Acetylcholine Receptors

Dopamine (DA) release in striatum is governed by firing rates of midbrain DA neurons, striatal cholinergic tone, and nicotinic ACh receptors (nAChRs) on DA presynaptic terminals. DA neurons selectively express α6* nAChRs, which show high ACh and nicotine sensitivity. To help identify nAChR subtypes...

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Main Authors: Drenan, Ryan M., Grady, Sharon R., Steele, Andrew D., McKinney, Sheri, Patzlaff, Natalie E., McIntosh, J. Michael, Marks, Michael J., Miwa, Julie M., Lester, Henry A.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390922/
https://ncbi.nlm.nih.gov/pubmed/20660270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2056-10.2010
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