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Insulin-degrading enzyme is exported via an unconventional protein secretion pathway
Insulin-degrading enzyme (IDE) is a ubiquitously expressed zinc-metalloprotease that degrades several pathophysiologically significant extracellular substrates, including insulin and the amyloid β-protein (Aβ), and accumulating evidence suggests that IDE dysfunction may be operative in both type 2 d...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632642/ https://ncbi.nlm.nih.gov/pubmed/19144176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-4-4 |
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