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Leishmania donovani Ornithine Decarboxylase Is Indispensable for Parasite Survival in the Mammalian Host

Mutations within the polyamine biosynthetic pathway of Leishmania donovani, the etiological agent of visceral leishmaniasis, confer polyamine auxotrophy to the insect vector or promastigote form of the parasite. However, whether the infectious or amastigote form of the parasite requires an intact po...

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Detalles Bibliográficos
Main Authors: Boitz, Jan M., Yates, Phillip A., Kline, Chelsey, Gaur, Upasna, Wilson, Mary E., Ullman, Buddy, Roberts, Sigrid C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632046/
https://ncbi.nlm.nih.gov/pubmed/19064633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01236-08
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