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Linker Histone Phosphorylation Regulates Global Timing of Replication Origin Firing

Despite the presence of linker histone in all eukaryotes, the primary function(s) of this histone have been difficult to clarify. Knock-out experiments indicate that H1s play a role in regulation of only a small subset of genes but are an essential component in mouse development. Here, we show that...

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Bibliographic Details
Main Authors: Thiriet, Christophe, Hayes, Jeffrey J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631944/
https://ncbi.nlm.nih.gov/pubmed/19015270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805617200
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