Stepwise Evolution of the Herpes Simplex Virus Origin Binding Protein and Origin of Replication

The herpes simplex virus replicon consists of cis-acting sequences, oriS and oriL, and the origin binding protein (OBP) encoded by the UL9 gene. Here we identify essential structural features in the initiator protein OBP and the replicator sequence oriS, and we relate the appearance of these motifs...

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Main Authors: Olsson, Monica, Tang, Ka-Wei, Persson, Cecilia, Wilhelmsson, L. Marcus, Billeter, Martin, Elias, Per
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713539/
https://ncbi.nlm.nih.gov/pubmed/19351883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807551200
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