The Potential Role of PUMA in Delayed Death of Hippocampal CA1 Neurons After Transient Global Cerebral Ischemia

BACKGROUND AND PURPOSE: p53-upregulated modulator of apoptosis (PUMA), a BH3-only member of the Bcl-2 protein family, is required for p53-dependent and -independent forms of apoptosis. PUMA localizes to mitochondria and interacts with anti-apoptotic Bcl-2 and Bcl-X(L) or pro-apoptotic Bax in respons...

Full description

Saved in:
Bibliographic Details
Main Authors: Niizuma, Kuniyasu, Endo, Hidenori, Nito, Chikako, Myer, D. Jeannie, Chan, Pak H.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631621/
https://ncbi.nlm.nih.gov/pubmed/19095966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.524447
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items