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The Potential Role of PUMA in Delayed Death of Hippocampal CA1 Neurons After Transient Global Cerebral Ischemia
BACKGROUND AND PURPOSE: p53-upregulated modulator of apoptosis (PUMA), a BH3-only member of the Bcl-2 protein family, is required for p53-dependent and -independent forms of apoptosis. PUMA localizes to mitochondria and interacts with anti-apoptotic Bcl-2 and Bcl-X(L) or pro-apoptotic Bax in respons...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631621/ https://ncbi.nlm.nih.gov/pubmed/19095966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.524447 |
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