Mitochondrial Translocation of p53 Mediates Release of Cytochrome c and Hippocampal CA1 Neuronal Death after Transient Global Cerebral Ischemia in Rats

Although p53 is a key modulator of cellular stress responses, the mechanism of p53-mediated apoptosis is ambiguous. p53 can mediate apoptosis in response to death stimuli by transcriptional activation of proapoptotic genes and transcriptional-independent mechanisms. Recent studies have shown that th...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Endo, Hidenori, Kamada, Hiroshi, Nito, Chikako, Nishi, Tatsuro, Chan, Pak H.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2006
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674216/
https://ncbi.nlm.nih.gov/pubmed/16870742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0897-06.2006
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