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ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replications forks and contribute to drug resistance
The Mre11-Rad50-Nbs1 complex and autophosphorylated Ser(1981)-ATM are involved in recognizing and repairing DNA damage, such as double-strand breaks (DSBs). However, the role of these factors in response to stalled replication forks is not clear. Nucleoside analogues are agents that are incorporated...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631429/ https://ncbi.nlm.nih.gov/pubmed/18829552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0971 |
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