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HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors

HIC1 (Hypermethylated In Cancer 1), as it name implied, was originally isolated as a new candidate tumor suppressor gene located at 17p13.3 because it resides in a CpG island that is hypermethylated in many types of human cancers. HIC1 encodes a transcription factor associating an N-terminal BTB/POZ...

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Detalhes bibliográficos
Main Authors: Fleuriel, Capucine, Touka, Majid, Boulay, Gaylor, Guérardel, Cateline, Rood, Brian R, Leprince, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631403/
https://ncbi.nlm.nih.gov/pubmed/18723112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2008.05.028
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