The Human Candidate Tumor Suppressor Gene HIC1 Recruits CtBP through a Degenerate GLDLSKK Motif

HIC1 (hypermethylated in cancer) and its close relative HRG22 (HIC1-related gene on chromosome 22) encode transcriptional repressors with five C(2)H(2) zinc fingers and an N-terminal BTB/POZ autonomous transcriptional repression domain that is unable to recruit histone deacetylases (HDACs). Alignmen...

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Main Authors: Deltour, Sophie, Pinte, Sébastien, Guerardel, Cateline, Wasylyk, Bohdan, Leprince, Dominique
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Transcriptional Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC133903/
https://ncbi.nlm.nih.gov/pubmed/12052894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4890-4901.2002
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