Disruption of Tissue-Specific Fucosyltransferase VII, an Enzyme Necessary for Selectin Ligand Synthesis, Suppresses Atherosclerosis in Mice

A hallmark feature of atherosclerosis is that circulating mononuclear cells adhere to the endothelium and migrate into the subendothelial space. This adhesion is mediated by molecules such as selectins that are expressed on the surfaces of both leukocytes and endothelial cells. In this study, we hav...

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Hlavní autoři: Gitlin, Jonathan M., Homeister, Jonathon W., Bulgrien, Joshua, Counselman, Jessica, Curtiss, Linda K., Lowe, John B., Boisvert, William A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631346/
https://ncbi.nlm.nih.gov/pubmed/19056851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080036
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