Disruption of Tissue-Specific Fucosyltransferase VII, an Enzyme Necessary for Selectin Ligand Synthesis, Suppresses Atherosclerosis in Mice

A hallmark feature of atherosclerosis is that circulating mononuclear cells adhere to the endothelium and migrate into the subendothelial space. This adhesion is mediated by molecules such as selectins that are expressed on the surfaces of both leukocytes and endothelial cells. In this study, we hav...

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Autores principales: Gitlin, Jonathan M., Homeister, Jonathon W., Bulgrien, Joshua, Counselman, Jessica, Curtiss, Linda K., Lowe, John B., Boisvert, William A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2009
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631346/
https://ncbi.nlm.nih.gov/pubmed/19056851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080036
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