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Generalized ensemble methods for de novo structure prediction

Current methods for predicting protein structure depend on two interrelated components: (i) an energy function that should have a low value near the correct structure and (ii) a method for searching through different conformations of the polypeptide chain. Identification of the most efficient search...

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Detalhes bibliográficos
Main Authors: Shmygelska, Alena, Levitt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631076/
https://ncbi.nlm.nih.gov/pubmed/19171891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812510106
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