Voluntary exercise prevents the obese and diabetic metabolic syndrome of the melanocortin-4 receptor knockout mouse

Exercise is a mechanism for maintenance of body weight in humans. Morbidly obese human patients have been shown to possess single nucleotide polymorphisms in the melanocortin-4 receptor (MC4R). MC4R knockout mice have been well characterized as a genetic model that possesses phenotypic metabolic dis...

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Main Authors: Haskell-Luevano, Carrie, Schaub, Jay W., Andreasen, Amy, Haskell, Kim R., Moore, Marcus C., Koerper, Lorraine M., Rouzaud, Francois, Baker, Henry V., Millard, William J., Walter, Glenn, Litherland, S. A., Xiang, Zhimin
Format: Artigo
Sprog:Inglês
Udgivet: The Federation of American Societies for Experimental Biology 2009
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630780/
https://ncbi.nlm.nih.gov/pubmed/18971258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-109686
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