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Pharmacological Characterization of 30 Human Melanocortin-4 Receptor Polymorphisms with the Endogenous Proopiomelanocortin Derived Agonists, Synthetic Agonists, and the Endogenous Agouti-Related Protein (AGRP) Antagonist

The melanocortin-4 receptor (MC4R) is a G-protein coupled receptor (GPCR) that is expressed in the central nervous system and has a role in regulating feeding behavior, obesity, energy homeostasis, male erectile response, and blood pressure. Since the report of the MC4R knockout mouse in 1997, the f...

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Detalhes bibliográficos
Main Authors: Xiang, Zhimin, Proneth, Bettina, Dirain, Marvin L., Litherland, Sally A., Haskell-Luevano, Carrie
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888279/
https://ncbi.nlm.nih.gov/pubmed/20462274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100068u
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