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Regulation of Telomerase Activity by Interferon Regulatory Factors 4 and 8 in Immune Cells

Telomerase activity is downregulated in somatic cells but is upregulated during the activation of cells of the immune system. The mechanism of this reactivation is not well understood. In this study, we demonstrated that interferon regulatory factor 4 (IRF-4) and, to a lesser extent, IRF-8 induce te...

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Detaylı Bibliyografya
Asıl Yazarlar: Hrdličková, Radmila, Nehyba, Jiří, Bose, Henry R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630682/
https://ncbi.nlm.nih.gov/pubmed/19047367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00961-08
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