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Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency against Escherichia coli In Vitro and In Vivo

The potency of antisense peptide-phosphorodiamidate morpholino oligomers (PPMOs) was improved by varying the peptide composition. An antisense phosphorodiamidate morpholino oligomer (PMO) complementary to the mRNA of the essential gene acpP (which encodes the acyl carrier protein required for lipid...

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Bibliografiset tiedot
Päätekijät: Mellbye, Brett L., Puckett, Susan E., Tilley, Luke D., Iversen, Patrick L., Geller, Bruce L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630659/
https://ncbi.nlm.nih.gov/pubmed/19015356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00917-08
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