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Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency against Escherichia coli In Vitro and In Vivo

The potency of antisense peptide-phosphorodiamidate morpholino oligomers (PPMOs) was improved by varying the peptide composition. An antisense phosphorodiamidate morpholino oligomer (PMO) complementary to the mRNA of the essential gene acpP (which encodes the acyl carrier protein required for lipid...

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Xehetasun bibliografikoak
Egile Nagusiak: Mellbye, Brett L., Puckett, Susan E., Tilley, Luke D., Iversen, Patrick L., Geller, Bruce L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630659/
https://ncbi.nlm.nih.gov/pubmed/19015356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00917-08
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