Removal of FKBP12 Enhances mTOR-Raptor Interactions, LTP, Memory, and Perseverative/Repetitive Behavior

FK506 binding protein 12 (FKBP12) binds the immunosuppressant drugs FK506 and rapamycin and regulates several signaling pathways, including mammalian target of rapamycin (mTOR) signaling. We determined whether the brain-specific disruption of the FKBP12 gene altered mTOR signaling, synaptic plastici...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hoeffer, Charles A., Tang, Wei, Wong, Helen, Santillan, Arturo, Patterson, Richard J., Martinez, Luis A., Tejada-Simon, Maria V., Paylor, Richard, Hamilton, Susan L., Klann, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630531/
https://ncbi.nlm.nih.gov/pubmed/19081378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.09.037
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados