Removal of FKBP12 Enhances mTOR-Raptor Interactions, LTP, Memory, and Perseverative/Repetitive Behavior

FK506 binding protein 12 (FKBP12) binds the immunosuppressant drugs FK506 and rapamycin and regulates several signaling pathways, including mammalian target of rapamycin (mTOR) signaling. We determined whether the brain-specific disruption of the FKBP12 gene altered mTOR signaling, synaptic plastici...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hoeffer, Charles A., Tang, Wei, Wong, Helen, Santillan, Arturo, Patterson, Richard J., Martinez, Luis A., Tejada-Simon, Maria V., Paylor, Richard, Hamilton, Susan L., Klann, Eric
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630531/
https://ncbi.nlm.nih.gov/pubmed/19081378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.09.037
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker