Novel Opioid Peptide Derived Antagonists Containing (2S)-2-Methyl-3-(2,6-dimethyl-4-carbamoylphenyl)propanoic Acid [(2S)-Mdcp]

A synthesis of the novel tyrosine analogue (2S)-2-methyl-3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid [(2S)-Mdcp] (15) was developed. In (2S)-Mdcp the amino- and hydroxyl groups of 2',6'-dimethyltyrosine are replaced by a methyl- and a carbamoyl group, respectively, and its substitutio...

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Hlavní autoři: Ghosh, Animesh, Luo, Jie, Liu, Chen, Weltrowska, Grazyna, Lemieux, Carole, Chung, Nga N., Lu, Yixin, Schiller, Peter W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630426/
https://ncbi.nlm.nih.gov/pubmed/18800771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8004702
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