A carregar...
Bimodal Recognition of DNA Geometry by Human Topoisomerase IIα: Preferential Relaxation of Positively Supercoiled DNA Requires Elements in the C-Terminal Domain
Human topoisomerase IIα, but not topoisomerase IIβ, can sense the geometry of DNA during relaxation and removes positive supercoils >10-fold faster than it does negative superhelical twists. In contrast, both isoforms maintain lower levels of DNA cleavage intermediates with positively supercoiled...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629653/ https://ncbi.nlm.nih.gov/pubmed/19053267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800453h |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|