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MDM2 is a novel E3 ligase for HIV-1 Vif
The human immunodeficiency virus type 1 (HIV-1) Vif plays a crucial role in the viral life cycle by antagonizing a host restriction factor APOBEC3G (A3G). Vif interacts with A3G and induces its polyubiquitination and subsequent degradation via the formation of active ubiquitin ligase (E3) complex wi...
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| Egile Nagusiak: | , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629459/ https://ncbi.nlm.nih.gov/pubmed/19128510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-1 |
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