Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin

Modification of proteins by the addition of lysine (K)-63-linked polyubiquitin (polyUb) chains is suggested to play important roles in a variety of cellular events, including DNA repair, signal transduction, and receptor endocytosis. However, identifying such modifications in living cells is complex...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Haopeng, Matsuzawa, Atsushi, Brown, Scott A., Zhou, JingRan, Guy, Cliff S., Tseng, Ping-Hui, Forbes, Karen, Nicholson, Thomas P., Sheppard, Paul W., Häcker, Hans, Karin, Michael, Vignali, Dario A. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629300/
https://ncbi.nlm.nih.gov/pubmed/19091944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810461105
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