Engineered Protein Connectivity to Actin Mimics PDZ-dependent Recycling of G Protein-coupled Receptors but Not Its Regulation by Hrs

Many G protein-coupled receptors (GPCRs) recycle after agonist-induced endocytosis by a sequence-dependent mechanism, which is distinct from default membrane flow and remains poorly understood. Efficient recycling of the β2-adrenergic receptor (β2AR) requires a C-terminal PDZ (PSD-95/Discs Large/ZO-...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Lauffer, Benjamin E. L., Chen, Stanford, Melero, Cristina, Kortemme, Tanja, von Zastrow, Mark, Vargas, Gabriel A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Mechanisms of Signal Transduction
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629119/
https://ncbi.nlm.nih.gov/pubmed/19001361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806370200
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items