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Strategies Targeting Telomerase Inhibition

Telomerase plays a pivotal role in cellular immortality and tumorigenesis. Its activity is normally not detectable in most somatic cells while it is reactivated in the vast majority of cancer cells. Therefore, inhibition of telomerase has been viewed as a promising anticancer approach due to its spe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chen, Huaping, Li, Yuanyuan, Tollefsbol, Trygve O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628964/
https://ncbi.nlm.nih.gov/pubmed/18956258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-008-9117-9
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