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Strategies Targeting Telomerase Inhibition

Telomerase plays a pivotal role in cellular immortality and tumorigenesis. Its activity is normally not detectable in most somatic cells while it is reactivated in the vast majority of cancer cells. Therefore, inhibition of telomerase has been viewed as a promising anticancer approach due to its spe...

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Detalhes bibliográficos
Main Authors: Chen, Huaping, Li, Yuanyuan, Tollefsbol, Trygve O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628964/
https://ncbi.nlm.nih.gov/pubmed/18956258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-008-9117-9
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