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Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms

Genistein, a natural isoflavone found in soybean products, has been reported to down-regulate telomerase activity and that this prevents cancer and contributes to the apoptosis of cancer cells. However, the precise molecular mechanism by which genistein represses telomerase is not clear. Here, we sh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Yuanyuan, Liu, Liang, Andrews, Lucy G., Tollefsbol, Trygve O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995334/
https://ncbi.nlm.nih.gov/pubmed/19358274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24398
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