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Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks

BACKGROUND: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications, changes in chromatin structure and patterns of DNA methylation across entire genomes. In these experiments, chromatin i...

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Библиографические подробности
Главные авторы: Nix, David A, Courdy, Samir J, Boucher, Kenneth M
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628906/
https://ncbi.nlm.nih.gov/pubmed/19061503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-523
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