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Active promoters give rise to false positive ‘Phantom Peaks’ in ChIP-seq experiments
Chromatin immunoprecipitation (ChIP) is widely used to identify chromosomal binding sites. Chromatin proteins are cross-linked to their target sequences in living cells. The purified chromatin is sheared and the relevant protein is enriched by immunoprecipitation with specific antibodies. The co-pur...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538825/ https://ncbi.nlm.nih.gov/pubmed/26117547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv637 |
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