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Active promoters give rise to false positive ‘Phantom Peaks’ in ChIP-seq experiments
Chromatin immunoprecipitation (ChIP) is widely used to identify chromosomal binding sites. Chromatin proteins are cross-linked to their target sequences in living cells. The purified chromatin is sheared and the relevant protein is enriched by immunoprecipitation with specific antibodies. The co-pur...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538825/ https://ncbi.nlm.nih.gov/pubmed/26117547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv637 |
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