Extensive HLA class I allele promiscuity among viral CTL epitopes

Promiscuous binding of T helper epitopes to MHC class II molecules has been well established, but few examples of promiscuous class I restricted epitopes exist. To address the extent of promiscuity of HLA class I peptides, responses to 242 well-defined viral epitopes were tested in 100 subjects rega...

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Main Authors: Frahm, Nicole, Yusim, Karina, Suscovich, Todd J., Adams, Sharon, Sidney, John, Hraber, Peter, Hewitt, Hannah S., Linde, Caitlyn H., Kavanagh, Daniel G., Woodberry, Tonia, Henry, Leah M., Faircloth, Kellie, Listgarten, Jennifer, Kadie, Carl, Jojic, Nebojsa, Sango, Kaori, Brown, Nancy V., Pae, Eunice, Zaman, M. Tauheed, Bihl, Florian, Khatri, Ashok, John, Mina, Mallal, Simon, Marincola, Francesco M., Walker, Bruce D., Sette, Alessandro, Heckerman, David, Korber, Bette T., Brander, Christian
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628559/
https://ncbi.nlm.nih.gov/pubmed/17705138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737365
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