Extensive HLA class I allele promiscuity among viral CTL epitopes

Promiscuous binding of T helper epitopes to MHC class II molecules has been well established, but few examples of promiscuous class I restricted epitopes exist. To address the extent of promiscuity of HLA class I peptides, responses to 242 well-defined viral epitopes were tested in 100 subjects rega...

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Bibliografische gegevens
Hoofdauteurs: Frahm, Nicole, Yusim, Karina, Suscovich, Todd J., Adams, Sharon, Sidney, John, Hraber, Peter, Hewitt, Hannah S., Linde, Caitlyn H., Kavanagh, Daniel G., Woodberry, Tonia, Henry, Leah M., Faircloth, Kellie, Listgarten, Jennifer, Kadie, Carl, Jojic, Nebojsa, Sango, Kaori, Brown, Nancy V., Pae, Eunice, Zaman, M. Tauheed, Bihl, Florian, Khatri, Ashok, John, Mina, Mallal, Simon, Marincola, Francesco M., Walker, Bruce D., Sette, Alessandro, Heckerman, David, Korber, Bette T., Brander, Christian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628559/
https://ncbi.nlm.nih.gov/pubmed/17705138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737365
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