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Regulation of centrosomes by the BRCA1-dependent ubiquitin ligase

Centrosomes are the organelles that organize microtubule networks and establish the bipolar mitotic spindle, which is essential for the segregation of chromosomes during cell division. Proper duplication of centrosomes is necessary to prevent genetic instability, thus control of this organelle is im...

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Bibliographic Details
Main Authors: Kais, Zeina, Parvin, Jeffrey D.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628548/
https://ncbi.nlm.nih.gov/pubmed/18927495
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