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BRCA1-Dependent Ubiquitination of γ-Tubulin Regulates Centrosome Number
Proper centrosome duplication and spindle formation are crucial for prevention of chromosomal instability, and BRCA1 plays a role in this process. In this study, transient inhibition of BRCA1 function in cell lines derived from mammary tissue caused rapid amplification and fragmentation of centrosom...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516733/ https://ncbi.nlm.nih.gov/pubmed/15367667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8457-8466.2004 |
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