Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis

Spontaneous mutants of Mycobacterium tuberculosis that were resistant to the anti-tuberculosis drugs ethionamide and isoniazid were isolated and found to map to mshA, a gene encoding the first enzyme involved in the biosynthesis of mycothiol, a major low-molecular-weight thiol in M. tuberculosis. Se...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Vilchèze, Catherine, Av-Gay, Yossef, Attarian, Rodgoun, Liu, Zhen, Hazbón, Manzour H, Colangeli, Roberto, Chen, Bing, Liu, Weijun, Alland, David, Sacchettini, James C, Jacobs, William R
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2008
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628429/
https://ncbi.nlm.nih.gov/pubmed/18651841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06365.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker