A Point Mutation in the Hair Cell Nicotinic Cholinergic Receptor Prolongs Cochlear Inhibition and Enhances Noise Protection

The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is what role(s) this feedback plays in our ability to he...

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Autori principali: Taranda, Julian, Maison, Stéphane F, Ballestero, Jimena A, Katz, Eleonora, Savino, Jessica, Vetter, Douglas E, Boulter, Jim, Liberman, M. Charles, Fuchs, Paul A, Elgoyhen, A. Belén
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628405/
https://ncbi.nlm.nih.gov/pubmed/19166271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000018
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