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Linopirdine Blocks α9α10-Containing Nicotinic Cholinergic Receptors of Cochlear Hair Cells

Studies of the electrophysiological response to acetylcholine (ACh) in mammalian outer hair cells (OHCs) are hindered by the presence of a large potassium current, I(K,n), most likely mediated by channels containing the KCNQ4 subunit. Since I(K,n) can be blocked by linopirdine, cholinergic effects m...

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Détails bibliographiques
Auteurs principaux: Gomez–Casati, María E., Katz, Eleonora, Glowatzki, Elisabeth, Lioudyno, María I., Fuchs, Paul, Elgoyhen, A. Belén.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504548/
https://ncbi.nlm.nih.gov/pubmed/15492885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-004-4025-6
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